Seven Arsenal players may not be up for selection when the Gunners take on Bournemouth in the FA Cup fourth round fixture at Dean Court.
Head coach Mikel Arteta will be without captain Pierre-Emerick Aubameyang and defender, David Luiz due to suspension.
Greek defender Sokratis is also a doubt with illness, though the former Dortmund defender returned to training on Friday.
Sead Kolasinac and Reiss Nelson are expected to return after the Premier League winter break next month.
A club statement read: “Pierre-Emerick Aubameyang – Suspended. Further to receiving a red card at Crystal Palace (a) on January 11, suspended for Monday’s game at Bournemouth.
“Calum Chambers – Left knee. Ruptured anterior cruciate ligament of his left knee during Chelsea (h) on December 29. Successful surgery completed. Rehabilitation process expected to take between six and nine months.
“Sead Kolasinac – Left thigh strain. Hoping to return to full training in the winter break period after Burnley (a) on February 2.
“David Luiz – Suspended. Further to receiving red card at Chelsea (a) on January 21, suspended for Monday’s game at Bournemouth.
“Reiss Nelson – Right hamstring. Hoping to return to full training in the winter break period after Burnley (a) on February 2.
“Sokratis – Back in full training further to illness. Being assessed ahead of Bournemouth (a).
“Kieran Tierney – Right shoulder. Dislocated right shoulder during West Ham Utd (a) on December 9. Successful surgery completed. Good progress being made in rehabilitation process with participation in regular outdoor fitness sessions. Aiming to return to full training in March.”